"The separate meta-analyses of fluoride gel or mouthrinse combined with toothpaste versus toothpaste alone favour the combined regimens, but differences were not statistically significant; the significant difference in favour of the combined use of fluoride varnish and toothpaste accrues from a very small trial and appears likely to be a spurious result. [Except for two studies finding gel + mouthrinse to be more effective than gel alone,] no other combinations of topical fluoride therapy were consistently superior to a single therapy."
Since fluoride can harm brains, kidneys, and more at certain doses, I'm glad people are interested in which therapies are most effective and are seeking the optimal exposure level.
"The separate meta-analyses of fluoride gel or mouthrinse combined with toothpaste versus toothpaste alone favour the combined regimens, but differences were not statistically significant; the significant difference in favour of the combined use of fluoride varnish and toothpaste accrues from a very small trial and appears likely to be a spurious result. [Except for two studies finding gel + mouthrinse to be more effective than gel alone,] no other combinations of topical fluoride therapy were consistently superior to a single therapy."
Since fluoride can harm brains, kidneys, and more at certain doses, I'm glad people are interested in which therapies are most effective and are seeking the optimal exposure level.