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Yes and no, mostly "no".

There are functioning Microsoft Office trojans that can self-replicate through e-mail.

There was a largely harmless but extremely widespread trojan that did drive-by Java attacks on webpages.

Repeat the above for Flash vulnerabilities.

There was a largely harmless but extremely widespread trojan that masqueraded as a free antivirus package and guilt-tripped naive users into authenticating via Installer.app, the only programmatic way to get code onto a Mac.

Best practice in my reality:

- DO NOT INSTALL A VIDEO CODEC PACKAGE

- DO NOT RUN COPIED OR TORRENTED SOFTWARE

- Enable Firewall.

- Remove Adobe Acrobat Reader unless your PDF workflow absolutely requires it.

- Disable Java immediately. (uninstall it for extra credit)

- Make sure Flash is at the dead latest self-updating version and set to auto-update.

- Update all non-stock browsers to self-updating versions.

- Update Microsoft Office and allow it to check for updates weekly.

- Allow Software Update to do its thing weekly.



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