Can't say I've ever felt that massive corps and the people that work there are super productive. In many instances they seem less productive than government.
Even without nationwide economies of scale, Michigan regularly has businesses selling weed vape carts for <$10 apiece. I don't know how much cheaper we want the weed to be, honestly. It's already at least 10x cheaper than the cheapest alcoholic beverage on a buzz-for-buzz basis.
What SMB has the luxury of being notoriously unproductive? Economies of scale are very real and tend to make larger businesses more efficient, it's true, but you'll find that causes SMBs to be lean and mean to remain competitive.
Your implied point that prices will drop with the introduction of interstate competition and access to finance and interest by mega-corps is well taken. You are certainly correct, there.
Notwithstanding grey-market limitations, people have their motives for accepting the inefficiency of starting or staying small. Potential, for example.
Though maybe you want your drug dealers to be unproductive, for society's sake! I may take this back...