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It's no wonder that the field is populated by crackpots.

They are trying to solve a problem nobody is worried about and nobody has ever been worried about in the history of the human specie.

People who dedicate more than 5 minutes a day to the thought of living to 120 are the usual suspects: Bezos, Ellison, Thiel and so forth.

A reputable industry cannot emerge if you can count the potential clients on one hand.



Aubrey de Grey said in 2007 and earlier a lot of people alive then will live to be 1000.

It's a very catchy thought, but so were Theranos's blood tests. It's almost the perfect scam, way better than Theranos's...investors will all be dead before he's proven wrong.

(Cynical take)


Aubrey is going grey which would suggest to me if he is practising what he preaches, he's not mastered it yet. Maybe he needs to find out what this cancer drug is doing? https://www.theguardian.com/science/2017/jul/21/cancer-patie...

He also drinks alcohol, he likes a pint, so perhaps he doesn't know that alcohol dissolves fat soluble vitamins from the liver, which in excess can cause a vitamin A deficiency. What he has is he has done time like a prisoner at these things called university's which generally reward people for academic conformity, having a memory and being able to use logic to argue points when elephants in the room appear. I'm also remind big pharma sponsor uni's in a variety of legal but potentially ethically questionable ways.

Now it should be noted that scientists have known a purified diet shortens life span, so arguably diets which restrict your ability to eat a varied diet, like a shake of sorts, could be doing you more harm, than eating top quality food products and then adding some supplements on top, whilst trying to not over eat.

Anyway read what you like, this is just one of many amino acids and a right mix of opinion which sort of represents life and the medical experts in general. https://joshmitteldorf.scienceblog.com/2017/02/06/glycine-an... https://raypeatforum.com/community/threads/aging-in-human-mi... https://novoslabs.com/novos-anti-aging-longevity-supplement/... https://pubmed.ncbi.nlm.nih.gov/29136945/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002905/

There is loads to read up on Glycine too numerous to list here, and there are loads of mistakes in scientific studies which if you read enough you can start to spot.

But I will also put this up. https://en.wikipedia.org/wiki/Angus_Barbieri%27s_fast

He had the world record for fasting, there used to be a movement in the 50's in the US called the Hygienists (Herbert Shelton) which was about water only fasting.

Guinness make a good point about unsafe practices, you dont want to deplete your body of some things like Glutathione when fasting, which is something the Hygienists never considered and possibly didnt know back then either. http://loveandtruth.net/shelton-fasting.html

Other factors with water only fasting and Ketogenic diets is Ketoacidosis, too many ketones and the liver cant handle the increase in acetone, you know nail polish remover! LOL

This probably sums up our medical knowledge best, the graph in the top left of this link. https://pubmed.ncbi.nlm.nih.gov/?term=glycine&sort=date&ac=y...

An explosion of knowledge where perhaps AI and big data can spot things the existing experts have missed? Like where AI can spot the subconscious bias in judges presiding over parole board requests.

Other points include, what is being taught is not always up to date, who sets the course work and writes the books and some knowledge being practiced is decades out of date and is likely contributing to worse outcomes.

Supermarkets also control the health of the nation because they tell farmers what properties they want in the food they sell, so supermarkets could tell pig farmers, they dont want pigs with a couple of inches of back fat, so the pig farmer goes to the nutritionist, can you reduce back fat, and the nutritionist comes back with a pellet mix which will achieve that objective. Farmer is happy, he is only interested in meeting the supermarkets requirements. He also doesnt know if this pellet mix is affecting the nations health or not.

So this lab grown meat will be interesting, it could end up "meating" the minimum legal standard to be called meat missing amino acids and other chemicals which can be found in the cheapest traditional reared meats, or it could become like a super meat containing everything we need that we can contribute to rude health if supermarkets didnt have profit margins to meat.

Anyway a contentious subject none the less and a very complex one.


> He also drinks alcohol, he likes a pint, so perhaps he doesn't know that alcohol dissolves fat soluble vitamins from the liver, which in excess can cause a vitamin A deficiency.

Funny enough, when I met him in person in 2007, he was drinking a beer and commented that "it's hardly immortalist".


Are you really saying no one has ever worried about death? I'm pretty sure everyone has, including you.


By the time it comes naturally, around 80 y/o 90 tops it would be a relief...you'd be so tired after a lifetime of fighting and you'd be such a second class citizen and excluded from all the fun and the social relevance that you'd be looking forward to checking out.

People who worry about death due to old age in their future are always the type who live in such luxury or are at their apex , having exhausted all other worries (and also wrongly project that they'll be in that frame of mind 50 or 60 years down the road).

> Including you

I have no interest in just existing, I want to thrive. Considering that pragmatically speaking it's not possible to thrive at 90, I have no interest in watching other people thrive, so checking out seems like a natural way of solving the issue.


> By the time it comes naturally, around 80 y/o 90 tops it would be a relief...you'd be so tired after a lifetime of fighting and you'd be such a second class citizen and excluded from all the fun and the social relevance that you'd be looking forward to checking out.

Does not match reality. Where are the waves of senior suicides?


> Where are the waves of senior suicides?

Where is their enthusiasm for life?

Of course survival instinct does its job very well. It even prevents people who are in extreme pain from committing the extreme act, but nonetheless it's not really that people look forward to stuff at 90.

And why would you? If you are not completely gone mentally, you can observe yourself losing relevance by the minute, younger guns attacking you and filling the void.


But curing aging / death would obviously make it so that you _can_ thrive at 90. Besides, most people I know who are in that age bracket are quite happy.

>People who worry about death due to old age in their future are always the type who live in such luxury or are at their apex

Not in my experience. I think people in general prefer existing over not existing, no matter what age.


> Not in my experience. I think people in general prefer existing over not existing, no matter what age.

Existing sucks, you want to thrive, meaning having fun, novelty, winning, and generally being a boss.

When you are old you simply don't thrive, you don't have fun, all the novelty is gone, you lose all the times, you lose your swagger because you become extremely risk averse both in your behavior in the natural environment as well as social behavior when around other people.




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