Not without a lot of messing around. With Intel you can pretty much just straight install macOS + Clover + FakeSMC and you're golden. With Ryzen you have to start messing around with custom kernels, which means updates will break things and also means a lot of programs won't work.
Last I checked a lot of progress had been made, but you're unable to run any 32-bit applications and some software such as the Adobe Creative Suite simply won't run.
Going to give it one, single try... then I'm on to Linux as my primary. Will have a Windows VM for some work, and may keep a mac VM as well. Most of the stuff I do works fine in Linux, and it really looks like Manjaro and Pop_OS! have made a lot of progress beyond the general dev stuff I work on (mostly via Docker/Linux anyway).
Oh yea, I wouldn't want to do that. I use a hackintosh but with an intel CPU and it just works flawlessly except for the whole NVidia GPU holding me back.
Last I checked a lot of progress had been made, but you're unable to run any 32-bit applications and some software such as the Adobe Creative Suite simply won't run.