Not sure if there is a much quicker way than using a solid monolithic such as Django or Ruby on Rails.
I'm used to React.js and TypeScript/GraphQL server on the backend. I would use Netlify to quickly deploy React.js and Apex Up to deploy the server to AWS Lambda. Apex Up doesn't really use AWS Lambda in the normal way. It will create a reverse proxy and each AWS Lambda function is like a mini server a la Heroku.
I'm used to React.js and TypeScript/GraphQL server on the backend. I would use Netlify to quickly deploy React.js and Apex Up to deploy the server to AWS Lambda. Apex Up doesn't really use AWS Lambda in the normal way. It will create a reverse proxy and each AWS Lambda function is like a mini server a la Heroku.