Shameless plug: I had the same problem until I built a tool to solve it. Earlier I'd subscribe to everything on my feedreader, get swamped by my to-read list, only skim it half-heartedly, and occasionally wonder "how'd I miss that?" Now I can focus my feedreader on the 10-20 feeds I never want to miss anything from (Rands is on it), and I'll almost always be current on my reading there. The remaining 1000+ feeds I've moved to http://readwarp.com. Give it a whirl anytime you're done reading your usual haunts (HN, google reader, email, ..).